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Native and Oxidized Low-Density Lipoproteins Increase the Expression of the LDL Receptor and the LOX-1 Receptor, Respectively, in Arterial Endothelial Cells

Atherosclerotic artery disease is the major cause of death and an immense burden on healthcare systems worldwide. The formation of atherosclerotic plaques is promoted by high levels of low-density lipoproteins (LDL) in the blood, especially in the oxidized form. Circulating LDL is taken up by conven...

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Principais autores: Rusan Catar, Lei Chen, Hongfan Zhao, Dashan Wu, Julian Kamhieh-Milz, Christian Lücht, Daniel Zickler, Alexander W. Krug, Christian G. Ziegler, Henning Morawietz, Janusz Witowski
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-01-01
coleção:Cells
Assuntos:
atherosclerosis
endothelium
LDL
LDL receptor
LOX-1
AP-1
Acesso em linha:https://www.mdpi.com/2073-4409/11/2/204
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