Repositioning Lopinavir, an HIV Protease Inhibitor, as a Promising Antifungal Drug: Lessons Learned from <i>Candida albicans</i>—In Silico, In Vitro and In Vivo Approaches

The repurposing strategy was applied herein to evaluate the effects of lopinavir, an aspartic protease inhibitor currently used in the treatment of HIV-infected individuals, on the globally widespread opportunistic human fungal pathogen <i>Candida albicans</i> by using in silico, in vitro and in viv...

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Váldodahkkit:	André L. S. Santos, Lys A. Braga-Silva, Diego S. Gonçalves, Lívia S. Ramos, Simone S. C. Oliveira, Lucieri O. P. Souza, Vanessa S. Oliveira, Roberto D. Lins, Marcia R. Pinto, Julian E. Muñoz, Carlos P. Taborda, Marta H. Branquinha
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	MDPI AG 2021-05-01
Ráidu:	Journal of Fungi
Fáttát:	<i>Candida albicans</i> drug repurposing HIV protease inhibitors secreted aspartic proteases lopinavir virulence
Liŋkkat:	https://www.mdpi.com/2309-608X/7/6/424
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