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The role and mechanism of ERalpha(ERα) in atrazine-induced disorders of hepatic iron metabolism

Atrazine (ATR), a widely used herbicide, that can affect liver metabolism. This study explored how ATR impacted liver iron metabolism using Wistar rats and L02 cells exposed to ATR. This study revealed that ATR can inhibit the expression of ERα in hepatocytes, the ERα can directly bind to the promot...

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Principais autores: Haotang Zhao, Jiaxin Zhang, Tong Lu, Manting Hou, Yaqin Zheng, Ying Qiao, Xiaotong Wu, Shihao Lou, Yuezhu Zhang, Lin Ye
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-09-01
Serier:Ecotoxicology and Environmental Safety
Fag:
Atrazine
Iron metabolism
ERα
Hepcidin
Online adgang:http://www.sciencedirect.com/science/article/pii/S0147651325013995
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