Hereditary Colon Cancer: Lynch Syndrome

Lynch syndrome is the most common familial colorectal cancer syndrome. It is linked to germline mutations in one of four DNA mismatch repair (MMR) genes. A comprehensive family history is one important way to identify at-risk individuals. The elucidation of the molecular genetics of this syndrome ha...

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Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Gastroenterology Council for Gut and Liver 2010-06-01
Edice:	Gut and Liver
Témata:	lynch syndrome mismatch repair gene microsatellite instability immunohistochemistry hereditary nonpolyposis colon cancer colon cancer
On-line přístup:	http://gutnliver.org/journal/view.html?doi=10.5009/gnl.2010.4.2.151
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