A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity

Background: Nucleic acid amplification tests (NAATs) are widely used to diagnose tuberculosis (TB), but cannot discriminate live bacilli from dead bacilli. Live bacilli can be isolated by culture methods, but this is time-consuming. We developed a de novo TB diagnostic method that detects only live...

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Detalhes bibliográficos

Principais autores:	Wen-Hung Wang, Rikiya Takeuchi, Shu-Huei Jain, Yong-Huang Jiang, Sonoko Watanuki, Yoshiharu Ohtaki, Kazunari Nakaishi, Satoshi Watabe, Po-Liang Lu, Etsuro Ito
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-10-01
Colecção:	EBioMedicine
Assuntos:	Mycobacterium tuberculosis ELISA thio-NAD cycling MPT64 live bacilli detection
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352396420303832
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