Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLCγ1/JNK/NF-κB Pathway in MC3T3-E1 Cells

Advanced glycation end-products (AGEs) are increased under hyperglycemia in vivo and are associated with the onset of diabetes. According to previous studies, AGEs exacerbate inflammatory diseases. However, the mechanism by which AGEs aggravate osteoblast inflammation remains unknown. Therefore, the...

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Bibliografiske detaljer

Principais autores:	Natsuko Tanabe, Keiko Tomita, Soichiro Manaka, Risa Ichikawa, Tadahiro Takayama, Takayuki Kawato, Misae Ono, Yuma Masai, Akihisa Utsu, Naoto Suzuki, Shuichi Sato
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-05-01
Serier:	Cells
Fag:	AGEs LPS IL-1α S100A9 PGE<sub>2</sub> PLCγ1
Online adgang:	https://www.mdpi.com/2073-4409/12/10/1383
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