Nano-Rifabutin entrapment within glucan microparticles enhances protection against intracellular Mycobacterium tuberculosis

Recently, yeast-derived glucan particles (GP) have emerged as novel drug delivery agents that provide for receptor-mediated uptake by phagocytic cells expressing β-glucan receptors. In our previous study, we prepared GP loaded with high payload (40.5 + 1.9%) of rifabutin (RB) nano-particles [(RB-NPs...

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Principais autores:	Tarun K. Upadhyay, Nida Fatima, Akanksha Sharma, Deepak Sharma, Rolee Sharma
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-12-01
Colecção:	Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:	β-Glucan rifabutin nanoparticles innate immune response tuberculosis mycobactericidal effect
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/21691401.2018.1559180
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