Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage polarization and osteoclastogenesis

Extensive macrophage inflammatory responses and osteoclast formation are predominant during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small extracellular vesicles (MSC-sEV) have been shown to exert therapeutic effects on bone defects. However, cultured MSCs are typica...

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Autores principales:	Jun Tian, Weiyang Chen, Yuhua Xiong, Qianer Li, Siyi Kong, Mengjie Li, Chunfeng Pang, Yu Qiu, Zhezhen Xu, Qimei Gong, Xi Wei
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	KeAi Communications Co., Ltd. 2023-04-01
Colección:	Bioactive Materials
Materias:	Dental pulp stem cells Small extracellular vesicles Macrophage Osteoclast Inflammatory osteolysis
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2452199X2200425X
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