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Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus

Plasma cells (PCs) are responsible for the production of protective antibodies against infectious agents but they also produce pathogenic antibodies in autoimmune diseases, such as systemic lupus erythematosus (SLE). Traditionally, high affinity IgG autoantibodies are thought to arise through germin...

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Bibliografiske detaljer
Principais autores: Susan Malkiel, Ashley N. Barlev, Yemil Atisha-Fregoso, Jolien Suurmond, Betty Diamond
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-03-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00427/full
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