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Interactive dynamic modulation of antidepressant treatment response by serum interleukin-1β and Neuroticism at 12 weeks

Abstract This study examined how serum interleukin-1 beta (sIL-1β) interacts with the Big Five personality trait of Neuroticism to influence 12-week antidepressant treatment outcomes in patients with depressive disorders. Baseline measurements of sIL-1β and Neuroticism were obtained from 1086 partic...

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Autori principali: Yoo-Chae Kim, Sung-Gil Kang, Ju-Wan Kim, Hee-Ju Kang, Min Jhon, Ju-Yeon Lee, Sung-Wan Kim, Il-Seon Shin, Jae-Min Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-01-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-026-35097-1
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