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GCNT3 and ST3GAL1 expression correlates with HER2 status and MUC1/β-catenin/Cyclin D1 axis in breast cancer

Abstract The status of human epidermal growth factor receptor 2 (HER2) is a critical determinant of breast cancer progression and outcome, but the role of glycosylation in modulating HER2-related pathways remains poorly understood. Here, we examined the relationship between HER2 and the glycosyltran...

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Principais autores: Rohitesh Gupta, Indresh K Gopalsamy, Aisha Shigna Nadukkandy, Ankit Singh, Charan Raju Tangella, Liza Esther Alexander, Rekha A Nair, Marco Cordani, Lekha Dinesh Kumar
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:BMC Cancer
Fag:
Breast cancer
HER2 status
Glycosyltransferases
GCNT3
ST3GAL1
Glycosylation
Online adgang:https://doi.org/10.1186/s12885-026-15821-w
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