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Guanine nucleotide exchange factors and colon neoplasia

Despite many diagnostic and therapeutic advances, colorectal cancer (CRC) remains the second leading cause of cancer death for men and women in the United States. Alarmingly, for reasons currently unknown, the demographics of this disease have shifted towards a younger population. Hence, understandi...

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Hoofdauteurs: Lea-Pearl Njei, Natalia Sampaio Moura, Alyssa Schledwitz, Kelly Griffiths, Kunrong Cheng, Jean-Pierre Raufman
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-10-01
Reeks:Frontiers in Cell and Developmental Biology
Onderwerpen:
colorectal cancer
guanine nucleotide exchange factors
βPak-interacting exchange factor
GEF-H1
Tiam1
Rho GTPases
Online toegang:https://www.frontiersin.org/articles/10.3389/fcell.2024.1489321/full
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