Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion

Objective: Deletion of Translin (Tsn) from mice induces an unusual metabolic profile characterized by robust adiposity, normal body weight and glucose tolerance. Translin (TN) protein and its partner, trax (TX), form the TN/TX microRNA-degrading enzyme. Since the microRNA system plays a prominent ro...

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Principais autores:	Xiuping Fu, Aparna P. Shah, Zhi Li, Mengni Li, Kellie L. Tamashiro, Jay M. Baraban
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2020-10-01
coleção:	Molecular Metabolism
Assuntos:	Obesity Translin Trax microRNA degradation Adipogenesis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2212877820300879
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