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Enzymatic oxidation of substituted tryptamines catalysed by monoamine oxidase

The enzymatic deamination of 5-fl uorotryptamine and 5-hydroxytryptamine, 5-HT, catalysed by enzyme monoamine oxidase A (MAO-A, EC 1.4.3.4) was investigated using the kinetic (KIE) and solvent (SIE) isotope effects methods. The numerical values of deuterium isotope effects in the (1R) positions of 5...

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Principais autores: Dragulska Sylwia, Kańska Marianna
Format: Artigo
Sprog:Inglês
Udgivet: Sciendo 2014-08-01
Serier:Nukleonika
Fag:
monoamine oxidase (MAO)
tryptamine
serotonin
isotope effects
Online adgang:http://www.degruyter.com/view/j/nuka.2014.59.issue-3/nuka-2014-0015/nuka-2014-0015.xml?format=INT
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