Integrated Biomimetic 2D-LC and Permeapad^® Assay for Profiling the Transdermal Diffusion of Pharmaceutical Compounds

A comprehensive two-dimensional liquid chromatography platform (LC × LC) was developed and validated for dermal permeability studies. In this implementation, the two separation dimensions were applied to mimic the layered structure of human skin: a ceramide-like stationary phase in the first dimensi...

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Bibliografische gegevens

Hoofdauteurs:	Ilaria Neri, Craig Stevens, Giacomo Russo, Lucia Grumetto
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2026-01-01
Reeks:	Molecules
Onderwerpen:	skin permeation two-dimensional liquid chromatography (2D-LC) Permeapad<sup>®</sup> immobilised artificial membrane biomimetic chromatography
Online toegang:	https://www.mdpi.com/1420-3049/31/2/379
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