Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria

Abstract Targeting β-oxidation has been proposed as a strategy for shortening tuberculosis (TB) treatment by killing non-replicating Mycobacterium tuberculosis within granulomas where the pathogen relies on host-derived lipids. The protein EtfD is thought to couple β-oxidation of fatty acids with th...

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Hlavní autoři:	Gautier M Courbon, Vadim Makarov, Stewart T Cole, Dirk Schnapinger, Sabine Ehrt, John L Rubinstein
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer Nature 2026-03-01
Edice:	The EMBO Journal
Témata:	ETF-QO EtfD Beta Oxidation Mycobacteria Structure
On-line přístup:	https://doi.org/10.1038/s44318-026-00726-y
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