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Piezo1 Mechanosensitive Ion Channel Mediates Stretch-Induced Nppb Expression in Adult Rat Cardiac Fibroblasts

In response to stretch, cardiac tissue produces natriuretic peptides, which have been suggested to have beneficial effects in heart failure patients. In the present study, we explored the mechanism of stretch-induced brain natriuretic peptide (Nppb) expression in cardiac fibroblasts. Primary adult r...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Meike C. Ploeg, Chantal Munts, Frits W. Prinzen, Neil A. Turner, Marc van Bilsen, Frans A. van Nieuwenhoven
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2021-07-01
Schriftenreihe:Cells
Schlagworte:
mechanosensing
cardiac fibroblast
brain natriuretic peptide
piezo1
stretch
Online-Zugang:https://www.mdpi.com/2073-4409/10/7/1745
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