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Ripretinib in combination with tyrosine kinase inhibitor as a late-line treatment option for refractory gastrointestinal stromal tumors: two case reports and literature review

Background: This case report presents two clinical cases of metastatic refractory gastrointestinal stromal tumor (GIST) with treatment history of 6–14 years. The follow-up treatment of both cases comprised ripretinib dose escalation and its combination with other tyrosine kinase inhibitors (TKIs). T...

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Главные авторы: Yefan Zhang, Zhen Huang
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2023-05-01
Серии:Frontiers in Pharmacology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fphar.2023.1122885/full
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