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Protective Effects of 6-Gingerol on Cardiotoxicity Induced by Arsenic Trioxide Through AMPK/SIRT1/PGC-1α Signaling Pathway

Background and Objective: Arsenic trioxide (As2O3) induced cardiotoxicity to limit the clinical applications of the effective anticancer agent. 6-Gingerol (6G) is the main active ingredient of ginger, a food with many health benefits. The present study aims to investigate the potential pharmacologic...

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Kaydedildi:
Asıl Yazarlar: Xue Han, Yakun Yang, Muqing Zhang, Xi Chu, Bin Zheng, Chenxu Liu, Yucong Xue, Shengjiang Guan, Shijiang Sun, Qingzhong Jia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2022-04-01
Seri Bilgileri:Frontiers in Pharmacology
Konular:
AMPK/SIRT1/PGC-1α pathway
arsenic trioxide
cardiotoxicity
6-gingerol
oxidative stress
Online Erişim:https://www.frontiersin.org/articles/10.3389/fphar.2022.868393/full
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