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Enhanced Enterovirus D68 Replication in Neuroblastoma Cells Is Associated with a Cell Culture-Adaptive Amino Acid Substitution in VP1

ABSTRACT Since its emergence in the United States in 2014, enterovirus D68 (EV-D68) has been and is associated with severe respiratory diseases and acute flaccid myelitis. Even though EV-D68 has been shown to replicate in different neuronal cells in vitro, it is currently poorly understood which vir...

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Bibliographic Details
Main Authors: Syriam Sooksawasdi Na Ayudhya, Adam Meijer, Lisa Bauer, Bas Oude Munnink, Carmen Embregts, Lonneke Leijten, Jurre Y. Siegers, Brigitta M. Laksono, Frank van Kuppeveld, Thijs Kuiken, Corine GeurtsvanKessel, Debby van Riel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020-12-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/mSphere.00941-20
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