Hunting down NLRP3 inflammasome: An executioner of radiation-induced injury

Radiotherapy is one of the mainstream treatment modalities for several malignancies. However, radiation-induced injury to surrounding normal tissues limits its efficacy. The NLRP3 inflammasome is an essential mechanism of innate immunity that reacts to challenges from endogenous danger signals and p...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Han Cheng, Lingling Chen, Minchun Huang, Jin Hou, Zhifeng Chen, Xiaojun Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-10-01
coleção:	Frontiers in Immunology
Assuntos:	NLRP3 inflammasome inflammasome activation radiation injury therapeutic target ROS pyroptosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.967989/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!