Crosstalk Between the NLRP3 Inflammasome/ASC Speck and Amyloid Protein Aggregates Drives Disease Progression in Alzheimer’s and Parkinson’s Disease

Two key pathological hallmarks of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are the accumulation of misfolded protein aggregates and the chronic progressive neuroinflammation that they trigger. Numerous original research and reviews have provided a...

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Detalles Bibliográficos

Principais autores:	Jonathan Hulse, Kiran Bhaskar
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2022-02-01
Series:	Frontiers in Molecular Neuroscience
Assuntos:	inflammasomes NLRP3 ASC Alzheimer’s disease Parkinson’s disease protein aggregation
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fnmol.2022.805169/full
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