Causal pathways linking polycystic ovary syndrome to distinct breast cancer subtypes through mediator factors: a multivariable mendelian randomization analysis

Abstract Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by ovarian cysts, high androgen levels, and irregular menstruation. The causality between PCOS and breast cancer (BC) has been widely discussed as they share a significant intersection in clinical manifestations. Previo...

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Detalhes bibliográficos

Principais autores:	Runxiang Cao, Lanlan Chen, Yutong Liu, Xuyutian Wang, Ruolin Ma, Qian Zhao, Ye Du
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-11-01
Colecção:	Journal of Ovarian Research
Assuntos:	Polycystic ovary syndrome Estrogen receptor-positive breast cancer Multivariable mendelian randomization analysis Age at menopause
Acesso em linha:	https://doi.org/10.1186/s13048-023-01306-y
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