Hypoxia induces PDK4 gene expression through induction of the orphan nuclear receptor ERRγ.

Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to cope with the stress imposed by a reduced oxygen env...

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Detalhes bibliográficos

Principais autores:	Ja Hee Lee, Eun-Jin Kim, Don-Kyu Kim, Ji-Min Lee, Seung Bum Park, In-Kyu Lee, Robert A Harris, Mi-Ock Lee, Hueng-Sik Choi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
Colecção:	PLoS ONE
Acesso em linha:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23050013/pdf/?tool=EBI
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