Cellf-deception: human microglia clone 3 (HMC3) cells exhibit more astrocyte-like than microglia-like gene expression

IntroductionRecent advances in Alzheimer’s research suggest that the brain’s immune system plays a critical role in the development and progression of this devastating disease. Microglial cells are vital as immune cells in the brain’s defense system. Human Microglia Clone 3 (HMC3) is a cell line dev...

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Principais autores:	Kylee K. Rahm, Branden S. Kinghorn, Myanna J. Moody, Ben C. Stone, Kenton C. Strong, Brian S. Kim, Yen Jou Chang, Samantha N. Sleight, Alyssa A. Nitz, David V. Hansen, Matthew H. Bailey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-11-01
Colecção:	Frontiers in Bioinformatics
Assuntos:	HMC3 cells iPSC-derived microglia (iMG) microglia astrocytes cell-type classification Alzheimer’s disease
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbinf.2025.1681811/full
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