Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

Background Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and comp...

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Detalhes bibliográficos

Principais autores:	Jie Li, Brandon A. Kemp, Nancy L. Howell, James Massey, Krzysztof Mińczuk, Qiao Huang, Mahendra D. Chordia, R. Jack Roy, James T. Patrie, Giovanni E. Davogustto, Christopher M. Kramer, Frederick H. Epstein, Robert M. Carey, Heinrich Taegtmeyer, Susanna R. Keller, Bijoy K. Kundu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2019-02-01
Colecção:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	hypertension hypertrophy/remodeling metabolic imaging myocardial metabolism rats
Acesso em linha:	https://www.ahajournals.org/doi/10.1161/JAHA.118.010926
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