Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier

Excessive neutrophil extravasation can drive immunopathology, exemplified in pyogenic meningitis caused by Streptococcus pneumoniae infection. Insufficient knowledge of the mechanisms that amplify neutrophil extravasation has limited innovation in therapeutic targeting of neutrophil mediated patholo...

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Autors principals:	Eliza Gil, Cristina Venturini, David Stirling, Carolin Turner, Liku B. Tezera, Giuseppe Ercoli, Tina Baker, Katharine Best, Jeremy S. Brown, Mahdad Noursadeghi
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	meningitis blood-brain barrier neutrophils pericytes macrophages Streptococcus pneumoniae
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.935798/full
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