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Programmed Aptamer Screening, Characterization, and Rapid Detection for α-Conotoxin MI

Conotoxins (CTXs) are a variety of mixed polypeptide toxins, among which α-conotoxin MI (CTX-MI) is the most toxic. Serious toxic symptoms, a lack of counteracting drugs, and cumbersome detection processes have made CTX-MI a hidden danger for humans. One of the obstacles to resolving this problem is...

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Principais autores: Han Guo, Bowen Deng, Luming Zhao, Yun Gao, Xiaojuan Zhang, Chengfang Yang, Bin Zou, Han Chen, Mingjuan Sun, Lianghua Wang, Binghua Jiao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-10-01
Serier:Toxins
Fag:
alpha-conotoxin MI (CTX-MI)
magnetic beads SELEX (MB-SELEX)
high-throughput sequencing (HTS)
aptamer
computer simulation
aptasensor
Online adgang:https://www.mdpi.com/2072-6651/14/10/706
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