Dynamic molecular and cellular characteristics of VSX2-positive retinal progenitor cells in human retinal organoids

Abstract Background The lack of understanding of the molecular and cellular characteristics of human retinal progenitor cells (RPCs) has hindered their application in cell therapy for retinal degenerative diseases. This study aims to employ retinal organoids (ROs) derived from a VSX2-enhanced green...

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Hlavní autoři:	Dandan Zheng, Yuan Wang, Yuanyuan Guan, Ping Xu, Bingbing Xie, Guanjie Gao, Xiaoming Yu, Fuhua Peng, Mengqing Xiang, Xiufeng Zhong
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-10-01
Edice:	Stem Cell Research & Therapy
Témata:	Retinal progenitor cell VSX2 Retinal organoid Cluster of differentiation biomarker Retinal degenerative disease Cell therapy
On-line přístup:	https://doi.org/10.1186/s13287-025-04700-z
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