Dynamic molecular and cellular characteristics of VSX2-positive retinal progenitor cells in human retinal organoids

Abstract Background The lack of understanding of the molecular and cellular characteristics of human retinal progenitor cells (RPCs) has hindered their application in cell therapy for retinal degenerative diseases. This study aims to employ retinal organoids (ROs) derived from a VSX2-enhanced green...

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Detalhes bibliográficos
Main Authors: Dandan Zheng, Yuan Wang, Yuanyuan Guan, Ping Xu, Bingbing Xie, Guanjie Gao, Xiaoming Yu, Fuhua Peng, Mengqing Xiang, Xiufeng Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-10-01
Colecção:Stem Cell Research & Therapy
Assuntos:
Retinal progenitor cell
VSX2
Retinal organoid
Cluster of differentiation biomarker
Retinal degenerative disease
Cell therapy
Acesso em linha:https://doi.org/10.1186/s13287-025-04700-z
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