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Impacts of the SOAT1 genetic variants and protein expression on HBV-related hepatocellular carcinoma

Abstract Background Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) remains a major public health problem and its pathogenesis remains unresolved. A recent proteomics study discovered a lipid enzyme Sterol O-acyltransferase (SOAT1) involvement in the progression of HCC. We aimed to ex...

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Main Authors: Yulong Chen, Xunjun Yang, Yao Chen, Guorong Chen, Cheryl A. Winkler, Ping An, Jianxin Lyu
Format: Artigo
Language:Inglês
Published: BMC 2021-05-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
SOAT1
Single nucleotide polymorphism
Susceptibility
Online Access:https://doi.org/10.1186/s12885-021-08245-1
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