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Statin shapes inflamed tumor microenvironment and enhances immune checkpoint blockade in non–small cell lung cancer

Immune checkpoint blockade (ICB) therapy has achieved breakthroughs in the treatment of advanced non–small cell lung cancer (NSCLC). Nevertheless, the low response due to immuno-cold (i.e., tumors with limited tumor-infiltrating lymphocytes) tumor microenvironment (TME) largely limits the applicatio...

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Principais autores: Wenjun Mao, Yun Cai, Danrong Chen, Guanyu Jiang, Yongrui Xu, Ruo Chen, Fengxu Wang, Xuehai Wang, Mingfeng Zheng, Xinyuan Zhao, Jie Mei
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical investigation 2022-09-01
סדרה:JCI Insight
נושאים:
Metabolism
Oncology
גישה מקוונת:https://doi.org/10.1172/jci.insight.161940
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