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Systematic characterization of pan‐cancer mutation clusters

Abstract Cancer genome sequencing has shown that driver genes can often be distinguished not only by the elevated mutation frequency but also by specific nucleotide positions that accumulate changes at a high rate. However, properties associated with a residue's potential to drive tumorigenesis when...

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Bibliographic Details
Main Authors: Marija Buljan, Peter Blattmann, Ruedi Aebersold, Michael Boutros
Format: Artigo
Language:Inglês
Published: Springer Nature 2018-03-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20177974
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