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CD49d- Treg Cells with High Suppressive Capacity are Remarkably Less Efficient on Activated CD45RA- than on Naive CD45RA+ Teff Cells

Background: Impairment of regulatory T cells (Tregs) in common autoimmune diseases seems likely. However, the extent of Treg deficiency (number, function) or differential susceptibility of T effector cells (Teffs) to suppression is not completely understood. We hypothesize that even in healthy indiv...

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Bibliografiske detaljer
Principais autores: Britta Kraczyk, Ralph Remus, Cornelia Hardt
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2014-07-01
Serier:Cellular Physiology and Biochemistry
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Online adgang:http://www.karger.com/Article/FullText/363004
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