APPlications of amyloid-β precursor protein metabolites in macrocephaly and autism spectrum disorder
Metabolites of the Amyloid-β precursor protein (APP) proteolysis may underlie brain overgrowth in Autism Spectrum Disorder (ASD). We have found elevated APP metabolites (total APP, secreted (s) APPα, and α-secretase adamalysins in the plasma and brain tissue of children with ASD). In this review, we...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2023-09-01
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| Serier: | Frontiers in Molecular Neuroscience |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/articles/10.3389/fnmol.2023.1201744/full |
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