Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4+, CD8+ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer

Abstract Background Dendritic cell (DC)-based immunotherapy is capable of activating the immune system and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. However, major limitations are the availability of autologous tumor cells as antigenic source and the selecti...

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Hlavní autoři:	Hemavathi Dhandapani, Hascitha Jayakumar, Abirami Seetharaman, Shirley Sunder Singh, Selvaluxmy Ganeshrajah, Nirmala Jagadish, Anil Suri, Rajkumar Thangarajan, Priya Ramanathan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-09-01
Edice:	Cancer Cell International
Témata:	SPAG9 Cisplatin Th1 IFNγ Immunotherapy Dendritic cells
On-line přístup:	https://doi.org/10.1186/s12935-021-01951-7
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