Isoflurane aggravates pre-existing proteotoxicity in adult nematodes by suppressing mitochondrial fitness

Abstract Post operative delirium (POD) is an acute complication, characterized by fluctuating attention and confusion, which may develop and persist into cognitive decline. POD is most commonly observed in elderly patients, particularly those with preexisting cognitive impairments. Isoflurane, a wid...

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Detalhes bibliográficos

Principais autores:	Tayir Elami, Huadong Zhu, Reut Bruck-Haimson, Vijigisha Srivastava, Adam Zaretsky, Irit Cohen, Einav Gross, Ehud Cohen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
coleção:	Scientific Reports
Assuntos:	Volatile anesthetics Isoflurane Proteostasis Aging Mitochondria C. elegans
Acesso em linha:	https://doi.org/10.1038/s41598-026-38591-8
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