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Breakthroughs in immune checkpoint therapy: overcoming NSCLC immune checkpoint therapy resistance with novel techniques

Immune checkpoint therapy has emerged as a revolutionary approach in the field of non-small cell lung cancer (NSCLC), offering new hope to patients with various malignancies. Despite its success, a significant proportion of patients exhibit primary or acquired resistance, limiting the efficacy of th...

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Principais autores: Li-Ping Kang, Hua-Jing Huang, Cong Xu, Hui-Hui Chen, Dong-Hui Huang, Ze-Bo Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-09-01
Serier:Frontiers in Immunology
Fag:
immune checkpoint inhibitors
NSCLC
resistance mechanisms
combination immunotherapy
epigenetic modifiers
personalized neoantigen vaccines
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1630940/full
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