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Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

Abstract: Fludarabine is the most frequently used agent in conditioning regimens for allogeneic hematopoietic cell transplantation (HCT). Body surface area–based dosing leads to highly variable fludarabine exposure. We studied the relation between fludarabine exposure and clinical outcomes. A retros...

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Autores principales: J.B. Langenhorst, C. van Kesteren, E.M. van Maarseveen, T.P.C. Dorlo, S. Nierkens, C.A. Lindemans, M.A. de Witte, A. van Rhenen, R. Raijmakers, M. Bierings, J. Kuball, A.D.R. Huitema, J.J. Boelens
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019-07-01
Colección:Blood Advances
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2473952920306510
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