Redefining post-stress depression as a spatiotemporal five-disease multimorbidity trajectory: ghrelin-driven anchoring by Shugan absorbed compounds

Aim: This study aimed to redefine post-stress depressive pathogenesis through a novel five-disease multimorbidity trajectory model (brain1-coronary-brain2-gastro-enteric; B1CB2GE) and to evaluate the multifunctional anchoring effects of Bupleurum chinense Shugan-San (BSS) and its absorbed compounds...

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Auteurs principaux:	Xi Huang, Runze Zhou, Chendong Xu, Haotian Qian, Yunke Huang, Zhan Gao, Qiulong Zhao, Min Xu, Shaoqi Shi, Ailing Yu, Jialing Zhou, Yaling Liu, Chenxiao Shan, Ping Ren
Format:	Artigo
Langue:	Inglês
Publié:	Open Exploration Publishing Inc. 2026-06-01
Collection:	Exploration of Neuroprotective Therapy
Sujets:	temporal multimorbidity trajectory acute forced swim normalization animal model multifunction
Accès en ligne:	https://www.explorationpub.com/uploads/Article/A1004159/1004159.pdf
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