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Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study

Abstract Background and Aims Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease (LEAD). Methods We included 39,713 patients with diabetes and...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng, Shumin Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-12-01
Schriftenreihe:Cardiovascular Diabetology
Schlagworte:
Primary aldosteronism
Lower-extremity arterial disease
Diabetes
Mendelian randomization
Causal relationship
Online-Zugang:https://doi.org/10.1186/s12933-023-02086-x
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