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Acquired Resistance to Afatinib Mediated by EGFR T790M in Lung Adenocarcinoma Patients Harboring EGFR-KDD: A Case Report and Literature Review

Epidermal growth factor receptor (EGFR)-kinase domain duplication (KDD) represents an atypical mutation distinct from classical EGFR mutations in lung adenocarcinoma (LUAD). Although first- and second-generation EGFR-tyrosine kinase inhibitors (TKIs) have demonstrated clinical activity in EGFR-KDD,...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Qian Liu, Lu Lv, Guanchao Pang, Pingli Wang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2026-04-01
Rangatū:Current Oncology
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1718-7729/33/4/214
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