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In vivo/ex vivo efficacy of artemether–lumefantrine and artesunate–amodiaquine as first-line treatment for uncomplicated falciparum malaria in children: an open label randomized controlled trial in Burkina Faso

Abstract Background Artemisinin-based combination therapy (ACT) is recommended to improve malaria treatment efficacy and limit drug-resistant parasites selection in malaria endemic areas. 5 years after they were adopted, the efficacy and safety of artemether–lumefantrine (AL) and artesunate–amodiaqu...

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Principais autores: Moussa Lingani, Léa Nadège Bonkian, Isidore Yerbanga, Adama Kazienga, Innocent Valéa, Hermann Sorgho, Jean Bosco Ouédraogo, Petronella Francisca Mens, Henk D. F. H. Schallig, Raffaella Ravinetto, Umberto d’Alessandro, Halidou Tinto
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-01-01
Serier:Malaria Journal
Fag:
Artemisinin-based combination therapy
In vivo/ex vivo
Efficacy
Safety
Uncomplicated malaria
Paediatric
Online adgang:https://doi.org/10.1186/s12936-019-3089-z
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