The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis

Abstract Objective Elamipretide (SS31) is a mitochondria-targeted peptide that has reported functions of stabilizing mitochondrial cristae structure and improving mitochondrial bioenergetics. Several studies have documented cell protective features of this peptide, including impairment of intrinsic...

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Bibliografski detalji

Glavni autori:	Joshua A. Grosser, Rachel L. Fehrman, Dennis Keefe, Martin Redmon, Robert W. Nickells
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2021-05-01
Serija:	BMC Research Notes
Teme:	BAX Intrinsic apoptosis Mitochondrial dysfunction Mitochondrial outer membrane permeabilization Mitochondrial fragmentation Elamipretide (SS31)
Online pristup:	https://doi.org/10.1186/s13104-021-05613-9
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