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Extreme MetaboHealth scores in three cohort studies associate with plasma protein markers for inflammation and cholesterol transport

Abstract The MetaboHealth score is an indicator of physiological frailty in middle aged and older individuals. The aim of the current study was to explore which molecular pathways co-vary with the MetaboHealth score. Using a Luminex cytokine assay and liquid chromatography-mass spectrometry-based pr...

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Principais autores: Daniele Bizzarri, Erik B. van den Akker, Marcel J. T. Reinders, René Pool, Marian Beekman, Nico Lakenberg, Nicolas Drouin, Kelly E. Stecker, Albert J. R. Heck, Edward F. Knol, Jeannette M. Vergeer, M. Arfan Ikram, Mohsen Ghanbari, Alain J. van Gool, Joris Deelen, BBMRI-NL, Dorret I. Boomsma, P. Eline Slagboom
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-09-01
Serier:Immunity & Ageing
Online adgang:https://doi.org/10.1186/s12979-025-00527-7
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