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New insights into mechanism of ellagic acid alleviating arsenic-induced oxidative stress through MAPK/keap1-Nrf2 signaling pathway response, molecular docking and metabolomics analysis in HepG2 cells

The increase of oxidative stress level is one of the vital mechanisms of liver toxicity induced by arsenic (As). Ellagic acid (EA) is widely known due to its excellent antioxidation. Nevertheless, whether EA could alleviate As-induced oxidative stress and the underlying mechanisms remain unknown. He...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Changhao Yu, Yawen Xu, Mengying Zhao, Ping Song, Jing Yu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-10-01
Saila:Ecotoxicology and Environmental Safety
Gaiak:
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S0147651324011059
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