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Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE

Inhibitors of the bacterial enzyme dapE-encoded <i>N</i>-succinyl-<span style="font-variant: small-caps;">l,l</span>-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonam...

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Xehetasun bibliografikoak
Egile Nagusiak: Cory T. Reidl, Tahirah K. Heath, Iman Darwish, Rachel M. Torrez, Maxwell Moore, Elliot Gild, Boguslaw P. Nocek, Anna Starus, Richard C. Holz, Daniel P. Becker
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2020-09-01
Saila:Antibiotics
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2079-6382/9/9/595
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