Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria

The toxicity of and resistance to platinum complexes as cisplatin, oxaliplatin or carboplatin calls for the replacement of these therapeutic agents in clinical settings. We have previously identified a set of half sandwich-type osmium, ruthenium and iridium complexes with bidentate glycosyl heterocy...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	István Kacsir, Adrienn Sipos, Tímea Kiss, Evelin Major, Nikolett Bajusz, Emese Tóth, Péter Buglyó, László Somsák, Gábor Kardos, Péter Bai, Éva Bokor
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-01-01
Schriftenreihe:	Frontiers in Chemistry
Schlagworte:	half-sandwich complex glycosyl triazole quinoline reactive oxygen species production ovarian cancer sarcoma
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fchem.2023.1086267/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!