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Mass spectrometry-based proteomics to study gastric carcinogenesis: pathophysiological molecular characterization

Abstract Gastric cancer (GC) remains a major global health challenge, ranking as the fifth most common malignancy. This study employs a proteomic approach to identify stage-specific proteomic signatures at different stages of gastric carcinogenesis, including chronic gastritis (CG), intestinal metap...

Deskribapen osoa

Gorde:
Egile Nagusiak: Nayra Felípez, Sheyla Montori, Alba Valero, Enrique Santamaría, Karina Ausin, Erika Peral, Joan Llach, Pedro Delgado, Pablo Florez-Diez, Eva Barreiro, Elena Arruebo, Raquel Vicente, MTeresa Soria, Alain Huerta, Silvia Patricia Ortega, Henar Núñez, Pilar Díez, Alberto Herreros, Gadea Hontoria, Rosa María Saiz, Luis Hernández, Carolina Mangas-Sanjuan, Oliver Patrón, Gonzalo Hijos-Mallada, María José Domper-Arnal, Sara Zarraquiños, Astrid Irene Díez-Martín, Patricia Gonçalves, Diego de Frutos, José Santiago, Adelina García, Alicia Martín-Lagos, Fermín Estremera-Arévalo, Marta Gómez-Alonso, Anabella Cuestas, Francesc Balaguer, Sergi Castellví-Bel, Glòria Fernandez-Esparrach, Miriam Cuatrecasas, Leticia Moreira, Joaquín Fernández-Irigoyen, Eduardo Albéniz, EpiGASTRIC EDGAR Consortium
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2026-07-01
Saila:Scientific Reports
Gaiak:
Gastric cancer
Proteomics
Premalignant lesions
NF-κB p65
p38MAPK
Sarrera elektronikoa:https://doi.org/10.1038/s41598-026-45298-3
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