Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure

Not just differential gene expression but also differential gene regulation in immune cells account for individual differences in the immune response. Authors show here by single-cell RNA-sequencing of peripheral blood mononuclear cells from a large cohort of genetically diverse individuals that gen...

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Podrobná bibliografie

Hlavní autoři:	Roy Oelen, Dylan H. de Vries, Harm Brugge, M. Grace Gordon, Martijn Vochteloo, single-cell eQTLGen consortium, BIOS Consortium, Chun J. Ye, Harm-Jan Westra, Lude Franke, Monique G. P. van der Wijst
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2022-06-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-022-30893-5
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