Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo

Amyotrophic Lateral Sclerosis (ALS), a late-onset neurodegenerative disorder characterized by the loss of motor neurons in the central nervous system, has no known cure to-date. Disease causing mutations in human Fused in Sarcoma (FUS) leads to aggressive and juvenile onset of ALS. FUS is a well-con...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Neha Gogia, Ankita Sarkar, Abijeet Singh Mehta, Ph.D., Nandini Ramesh, Prajakta Deshpande, Madhuri Kango-Singh, Udai Bhan Pandey, Amit Singh
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-07-01
Edice:	Neurobiology of Disease
Témata:	Neurodegeneration Amyotrophic Lateral Sclerosis (ALS) Fused in Sarcoma (FUS) Translocated in Liposarcoma (TLS) Drosophila eye Hippo pathway
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0969996120301121
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!